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Intelicaps Mono-Strains
1. Lactobacillus acidophilus
- 94 403 publications related from 2000 to 2025
- A recent study has demonstrated that even with the presence of other lactobacilli in the vaginal microbiota, the absence of L. acidophilus could lead to a lack of protection against bacterial vaginosis and aerobic vaginosis. (David Pacha-Herrera et al., 2022)
- Recent study drew attention again to the vaginal microbiota and identified L. acidophilus as one of the major strains found in healthy vagina. (Salinas et al., 2018).
- Most relevant clinical trials have suggested that oral or intra-vaginal administration of Lactobacillus acidophilus is able to increase the number of vaginal Lactobacilli, restore the vaginal microbiota to normal, and cure women of bacterial vaginosis (Falagas et al. 2007).
- Lactobacillus acidophilus is probably the best well-known species of Lactobacillus, this microorganism is naturally found in the human and animal gastrointestinal tract, mouth and vagina (DerMarderosian & Beutler 2002).
2. Bifidobacterium animalis subsp lactis
- 48 779 publications related from 2000 to 2025
- A clinical study was conducted on 27 persons (14 placebo group and 13 test group) from 52 to 64 years old. The studied persons had experienced transit disorders for several years (17.8± 15.4 years on average) and had episodes in the previous 2 weeks before the study. The treatment was taken twice per day for the first 5 days and then once per day for the next 25 days. After the treatment the number of days with abdominal discomfort was significantly decreased in the group treated with the symbiotic Cibalax (B. lactis + FOS). More persons taking the symbiotic reported a significantly or much improved perception of change about their transit. (Neyrinck et al., 2021)
- Uchida et al., observes a significant increase in stool frequency and Bifidobacterium proportion compared to the placebo. It was considered to be an effect of B.lactis Bb-12. There is no significant adverse events from higher ingestion. Bb-12 improves intestinal conditions. (Uchida et al., 2005)
3. Lactobacillus rhamnosus – Lacticaseibacillus rhamnosus
- 82 959 publications related from 2000 to 2025
- A recent study investigated that early-life LGG colonization could protect intestinal barrier of offspring and modulate gut-brain axis in association with relief of anxiety-like behavior in adulthood (Zhou et al., 2022)
- Another study on mice, investigated Clostridioides difficileinfection and administration of LGG in combination with the antibiotic Vancomycin. In the vancomycin combined with LGG model, it prevented weight loss, improved the histopathological scores, and effectively reduced the mortality. LGG + vancomycin administration promoted the recovery of the intestinal flora by inhibiting Enterococcus and counteracting the side effects of vancomycin treatment. In both the preventive and therapeutic CDI mouse models, the oral LGG strain showed the ability to protect against primary and recurrent infections, indicating that probiotics have potential for treating intestinal diseases (Wu et al., 2022)
- Lactobacillus rhamnosus GG is effective in reducing duration of acute diarrhoea in children and adults, and its effect depends on the dose administered and the timing of initiation of the treatment (the earlier, the better). The effect is highly significant among patients with watery diarrhoea and viral gastroenteritis. (Cincinnati ,2011)
- A systematic review and meta-analysis demonstrated that probiotics are effective therapies for IBS, in terms of both improvement in overall symptoms as a dichotomous measure and improvement in global symptom, abdominal pain, bloating, and flatulence scores. The NNT to improve one patient ’s symptoms was 7. Lactobacillus rhamnosus GG increases treatment success in children with abdominal pain-related functional gastrointestinal disorders, particularly among children with IBS. (Horvath,2011)
4. Lactobacillus reuteri – Limosilactobacillus reuteri
- 51 168 publications related from 2000 to 2025
- A recent clinical study observed the difference in the stool, vomiting-up, colic and other factors in the digestion of infants from 6 to 16 weeks comparing them while breastfed, formula fed and formula + L. reuteri fed. Their results showed that infants fed with formula containing L. reuteri had a better gastrointestinal tolerance than the ones fed with normal formula, less colic, less vomiting, better consistency of the stool (not too hard). The infants fed with the formula containing L. reuteri had a comparable gastrointestinal tolerance than the ones the were breastfed. (Happy Tummy Consortium et al., 2023)
- The study made by Vujic et al., consisted of a double -blind, randomized, placebo-controlled study including a total of 544 subjects. Included were women older than 18 years of age, diagnosed with vaginal infection. The results were significant on the beneficial effects of the administration or L. reuteri. After 44 days, restitution to balanced vaginal microbiota was reported in 40 subjects (26.9%) in the placebo group, compared to 243 subjects (61.5%) in the probiotic group. (Vujic et al., 2013)
5. Lactobacillus plantarum – Lactiplantibacillus plantarum
- 130 530 publications related from 2000 to 2025
- In its review, Seddik et al., analyses the beneficial properties of L. plantarum including its effect on IBS (Irritable Bowel Syndrome) (Seddik et al., 2017)
6. Lactobacillus casei – Lacticaseibacillus casei
- 86 319 publications related
Lai, H. H., Chiu, C. H., Kong, M. S., Chang, C. J., & Chen, C. C. (2019). Probiotic Lactobacillus casei: Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients, 11(5), 1150. https://doi.org/10.3390/nu11051150
Tormo Carnicer, R., Infante Piña, D., Roselló Mayans, E., & Bartolomé Comas, R. (2006). Efecto de la ingesta de leche fermentada con Lactobacillus casei DN-114 001 sobre la flora intestinal [Intake of fermented milk containing Lactobacillus casei DN-114 001 and its effect on gut flora]. Anales de pediatria (Barcelona, Spain : 2003), 65(5), 448–453. https://doi.org/10.1157/13094251
Our Blends
1. Woman Biotic Blend :
- Lactobacillus acidophilus
- Levilactobacillus brevis
- Lactobacillus crispatus
Woman’s Health
This premix contains 3 strains that work towards maintaining the equilibrium of the feminine flora. The link between the maintenance of a healthy vaginal flora and the presence of lactobacilli has been established for a long time (Butler et al., 1960).
Bacterial vaginosis is the most common vaginal infection in reproductive-age women (Kairys et al., 2022). Therefore maintaining a good amount of Lactobacilli in the feminine flora appears to be mandatory to avoid bacterial vaginosis. Our lactogyn premix aims in that direction by including three different strains of lactobacilli: L. acidophilus, L. brevis and L. crispatus that were identified as having a high colonization capacity of the vagina. They have a good adherence to the vaginal epithelial cells, produce H2O2 and therefore their combined action counteracts the adhesion/colonization of pathogens.
This premix has been studied in a phase 2 randomized (1:1 allocation ratio) interventional parallel group prospective placebo controlled multicenter clinical study. The results were extremely positive as the recurrence of bacterial vaginosis was two times lower in the group taking Lactogyn premix compared to the placebo group.
2. Kids Biotic Blend :
- Bifidobacterium animalis subsp lactis
- Bifidobacterium bifidum
- Bifidobacterium longum
- Bifidobacterium infantis
- Lacticaseibacillus rhamnosus
Intestinal flora’s health for infants
This premix contains 4 strains of bifidobacterial and 1 strain of lactobacillus for a total of 5 different strains.
The intestinal flora of the new-born baby develops in the first moments which follow the birth. Mode of childbirth, type of food (feeding-bottle or breast feeding), taken antibiotics, environment… are as many factors which influence the development of this intestinal flora. Any disturbance of the normal development of the intestinal flora can be the cause of various disorders.
Giving probiotics to new-born or infants/childs is advised and even more in case of diarrhea, colic and irritable bowel syndrome.
3. Gastro Biotic Blend (2 strains) :
- Bifidobacterium animalis subsp lactis
- Lacticaseibacillus rhamnosus
Intestinal flora’s health.
This premix contains 2 strains that work toward maintaining the equilibrium of the gut’s flora and preventing some symptoms.
Lacticaseibacillus rhamnosus has been studies in case of acute diarrhoea and antibiotic-associated diarrhoea and has been identifies as effective in reducing duration of acute diarrhoea in children and adults, and its effect depends on the dose administered and the timing of initiation of the treatment (the earlier, the better). The effect is highly significant among patients with watery diarrhoea and viral gastroenteritis. (Cincinnati ,2011)
This strain has also showed good results in reducing the abdominal pain particularly associated with irritable bowel syndrome (Horvath,2011).
On its part, Bifidobacterium animalis subsp lactis has also be studied in the case of antibiotics-associated diarrhoea with significant result in reducing the duration. A clinical study also proven that associated with a prebiotic, number of days with abdominal discomfort was significantly decreased in the group treated with the symbiotic. More persons taking the symbiotic reported a significantly or much improved perception of change about their transit. (Neyrinck et al., 2021)
This premix is therefore advised in case of treatment with antibiotics in order to restore the gut’s flora equilibrium and to reduce the diarrhoea that might be associated with the treatment. It allows also to relieve from intestinal discomfort.
4. Gastro Biotic Blend (3 strains) :
- Bifidobacterium animalis subsp lactis
- Lactiplantibacillus plantarum
- Lacticaseibacillus rhamnosus
Intestinal flora’s health.
This premix contains 3 strains strains that work toward maintaining the equilibrium of the gut’s flora and preventing some symptoms.
In addition to this two strains mentioned in Forte Premix (2 strains), L. plantarum has been added to this premix as it has also been studied with promising results on Irritable Bowel Syndrome and its capability of reducing its symptoms. (Seddik et al., 2017). Moreover, L. plantarum is also capable to produce bacteriocins that are extracted to be used a biopreservatives in foods and could therefore be used in fighting pathogens in the gut. (Behera et al., 2018)
5. Immunity Blend :
- Lacticaseibacillus rhamnosus
- Lactiplantibacillus plantarum
- Bifidobacterium animalis subsp lactis
Immunity health
This blend contains 3 strains specifically chosen for their effect on the enhancement of the immune system response.
These three specifics strains have demonstrated positive results on the immune response in diverse studies. This blend is recommended to be used to improve the immune response directly from the gut.
6. Digest Biotic Blend :
- Lacticaseibacillus rhamnosus
- Lactiplantibacillus plantarum
- Lacticaseibacillus casei
- Bifidobacterium animalis subsp lactis
- Bifidobacterium longum
IBS Health
This blend contains 5 strains specifically chosen for their action on the intestinal transit and their anti-constipation function.
A lot of articles and studies on these strains are oriented to the bowel movements with positive results. This is why this blend is recommended to be used for any discomfort, bloating, or digestive trouble.
7. Digest Biotic + Blend :
- Lacticaseibacillus rhamnosus
- Bifidobacterium animalis subsp lactis
- Bifidobacterium infantis
- Bifidobacterium bifidum
Intestinal flora’s health and digestion
This blend of 4 strains has been developped to relieve form intestinal discomfort.
These strains together work towards a better intestinal comfort by reducing abdominal pain, adjusting the stool frequency and reducing IBS symptoms.
8. Senior Biotic Blend :
- Lacticaseibacillus rhamnosus
- Lactiplantibacillus plantarum
- Lactobacillus acidophilus
- Lacticaseibacillus casei
- Bifidobacterium animalis subsp lactis
These different strains have proven their efficacy on inhibition of clositridum difficile that could induce diarrhoea.
Moreover they also have proven to their efficacy on the transit, their action on acute diarrhoae or antiobiotic-associated diarrhoea.
This blend has been designed toward senior who are more sensitive to antiobiotic-associated diarrhoea.
9. diaSTOP Biotic Blend :
- Lacticaseibacillus rhamnosus
- Lactiplantibacillus plantarum
- Lactobacillus acidophilus
- Bifidobacterium animalis subsp lactis
This blend is advised for preventing diarrhea associated to antiobiotcs, viral and bacterial diarrhea.
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